Ocular Disease — Posterior Retinal Diseases
1 / 10
1. The ‘bone spicule’ pigmentary deposits in retinitis pigmentosa are located:
RP: bone spicule pigmentation from migrated RPE cells along retinal vessels — found in the mid-peripheral retina.
2 / 10
2. Which investigation best evaluates the choroidal circulation?
ICG angiography (ICGA) uses near-infrared dye that penetrates the RPE better than fluorescein — ideal for choroidal vasculature (PCV, occult CNV, choroidal hemangioma).
3 / 10
3. The ‘sea-fan’ pattern of neovascularization in the retina periphery is seen in:
Sea-fan neovascularization in the peripheral retina is the hallmark of proliferative sickle cell retinopathy (HbSC > HbSS).
4 / 10
4. The primary treatment for rhegmatogenous retinal detachment is:
Rhegmatogenous RD: surgical repair — laser/cryo retinopexy + scleral buckle or pneumatic retinopexy or vitrectomy (PPV).
5 / 10
5. Neovascular (wet) AMD is treated with:
Wet AMD: anti-VEGF intravitreal injections (ranibizumab, bevacizumab, aflibercept) are first-line treatment — reduce CNV leakage and improve VA.
6 / 10
6. Stargardt disease primarily affects:
Stargardt disease: autosomal recessive (ABCA4 mutation) — most common inherited macular dystrophy. Progressive central vision loss in young patients.
7 / 10
7. Laser treatment for diabetic retinopathy (panretinal photocoagulation) aims to:
PRP destroys ischemic peripheral retinal tissue → reduces VEGF production → regression of neovascularization (NVD/NVE).
8 / 10
8. Age-related macular degeneration (AMD) in its dry form is characterized by:
Dry AMD: drusen (hard/soft), RPE atrophy, and geographic atrophy — slow progression, no CNV.
9 / 10
9. Central serous chorioretinopathy (CSCR) typically affects:
CSCR: subretinal fluid accumulation under the macula — typically affects young to middle-aged men, associated with stress and corticosteroid use.
10 / 10
10. Epiretinal membrane (ERM) causes:
ERM: fibrocellular proliferation on the inner retinal surface causing metamorphopsia (distortion), thickening, and reduced central VA.
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